As told in the opening introduction and in the episode "Creepie Crawling", Creepie was a waif left on the doorstep of the Dweezwold Mansion, which is home to a family of various insects. The family took her in and raised her as one of their own. She must now adjust to a life surrounded by a society of insectophobic humans as she attends Middlington Middle School and keeps her home life secret in order to protect both herself and her family.