OK K.O.! Let's Be Heroes follows the titular character, K.O., and his efforts to become the world's greatest hero while working at Gar's Bodega, a hero supply shop in the Lakewood Plaza strip mall. Alongside him are his best friends and co-workers Radicles, an apathetic, narcissistic alien, and Enid, a levelheaded big sister-like employee, as well as other heroes who work and frequent the area.